Honoring the science that protects health before it breaks down.
The mouth and nose are the front line of health. We honor the innovators restoring hygiene to its rightful place in medicine.

A Simple Truth We've Overlooked
For most of human history, the greatest advances in health didn't come from drugs or surgery.
They came from hygiene and sanitation.
Clean water. Waste removal. Handwashing. Oral care. Basic cleanliness practices. These simple interventions transformed human life—adding decades to lifespan, reducing child mortality, and preventing countless diseases before they ever began.
And yet today, hygiene has largely disappeared from the healthcare conversation. We spend trillions on reactive care but neglect the 30% of health gains attributable to hygiene—the most scalable, accessible, and cost-effective frontier in medicine.
Gateway Microbiomes
Where Disease Begins—and Where We Can Stop It
The oral and nasal cavities are the body's primary entry points. When their defenses fail, systemic disease follows.
The Oral Gateway
Linked to cardiovascular disease, diabetes, Alzheimer's, and emerging cancer research.
Explore the evidenceThe Nasal Gateway
The overlooked entry point for airborne pathogens. Key to respiratory defense.
Explore the evidence
The Call for Innovation
The next breakthrough in health may not come from a lab. It may come from a sink.
The Hygiene Innovation Prize recognizes scientists, clinicians, and innovators working to restore oral and nasal hygiene to the center of healthcare.
View Past Laureates
